Is Diffusion Tensor Imaging-Guided Radiotherapy the New State-of-the-Art? A Review of the Current Literature and Technical Insights

Despite the increasing precision of radiotherapy delivery, it is still frequently associated with neurological complications. This in part due to damage eloquent white matter (WM) tracts, which made more likely by fact they cannot be visualised on standard structural imaging. WM additionally vulnerable than grey radiation damage. Primary brain malignancies also are known spread along WM. Diffusion tensor imaging (DTI) only vivo method delineating tracts. DTI an technique that models direction diffusion and therefore can infer orientation fibres. review article evaluates current evidence for using guide intracranial whether constitutes a new state-of-the-art technique. We provide basic overview its applications radiotherapy, include tractography reduce dose tracts detect or predict tumoural spread. evaluate DTI-guided gliomas, metastatic disease, benign conditions, finding strongest use arteriovenous malformations. However, weak other conditions lack case-controlled trials.